INTRAOCULAR DAPIPRAZOLE FOR THE REVERSAL OF MYDRIASIS AFTER EXTRACAPSULAR CATARACT-EXTRACTION WITH INTRAOCULAR-LENS IMPLANTATION .1. DOSE-RESPONSE CORRELATION

被引：0

作者：

PONTE, F ^{[1
]}

CILLINO, S ^{[1
]}

FARANDA, F ^{[1
]}

CASANOVA, F ^{[1
]}

CUCCI, F ^{[1
]}

机构：

[1] POLICLIN PALERMO,OCULIST CLIN,VIA LIBORIO GIUFFRE 13,I-90127 PALERMO,ITALY

来源：

JOURNAL OF CATARACT AND REFRACTIVE SURGERY | 1991年 / 17卷 / 06期

关键词：

DOUBLE-BLIND STUDY; EXTRACAPSULAR CATARACT EXTRACTION; INTRAOCULAR DAPIPRAZOLE; INTRAOCULAR LENS IMPLANTATION; MIOSIS; MYDRIASIS;

D O I：

10.1016/S0886-3350(13)80411-7

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Dapiprazole, an alpha-blocking miotic drug, was used intracamerally at the end of extracapsular cataract extraction with posterior chamber intraocular lens (IOL) implantation. The double-blind study included 120 patients divided into four groups of 30 eyes; the groups received balanced salt solution, 0.125%, 0.25%, or 0.5% intraocular dapiprazole after IOL implantation and before suturing. Pupillary diameter recordings were performed immediately before and a few minutes after drug injection and two, four, and eight hours after surgery. The results showed a significant reversal of mydriasis by intraocular dapiprazole, especially with the 0.25% and 0.5% concentrations which did not differ significantly in effectiveness and safety.

引用

页码：780 / 784

页数：5

共 17 条

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