INTERLEUKIN-1, IMMUNE ACTIVATION PATHWAYS, AND DIFFERENT MECHANISMS IN OSTEOARTHRITIS AND RHEUMATOID-ARTHRITIS

被引:58
作者
KIRKHAM, B
机构
[1] Walter and Eliza Hail Institute of Medical Research, Post Office, Royal Melbourne Hospital
关键词
D O I
10.1136/ard.50.6.395
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Interleukin-1 seems to be important in the immunopathology of many forms of arthritis, and this has been increasingly recognised in the last few years. Its production is complicated and various inhibitors have been described. It is widely distributed, forming part of the network of cytokines, and seems to behave differently in osteoarthritis and rheumatoid arthritis. Perhaps these differences can be exploited.
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页码:395 / 400
页数:6
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