CORTICAL ATROPHY AND COGNITIVE PERFORMANCE IN INFANTILE NEPHROPATHIC CYSTINOSIS

被引：48
|
作者：
NICHOLS, SL [1 ]
PRESS, GA [1 ]
SCHNEIDER, JA [1 ]
TRAUNER, DA [1 ]
机构：
[1] UNIV CALIF SAN DIEGO,MED CTR,H-815-B,225 DICKINSON ST,SAN DIEGO,CA 92103
来源：
PEDIATRIC NEUROLOGY | 1990年 / 6卷 / 06期
关键词：
D O I：
10.1016/0887-8994(90)90004-K
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
A group of children and adolescents with infantile nephropathic cystinosis underwent cognitive testing and were examined for cortical atrophy using magnetic resonance imaging or computed tomography. Ten of 11 patients demonstrated cortical atrophy. A consistent pattern of lower cognitive performance was found in patients with greater atrophy; however, only the relationship between atrophy and short-term memory approached statistical significance. In addition, evidence for greater impairment of visual memory than of other cognitive functions was observed. This latter observation did not appear to be related to the degree of atrophy. © 1990.
引用
收藏
页码：379 / 381
页数：3
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