DNA TOPOISOMERASE POISONS AS ANTITUMOR DRUGS

[1] SELECTIVE INTERRUPTION OF HIGH MOLECULAR-WEIGHT RNA SYNTHESIS IN HELA-CELLS BY CAMPTOTHECIN [J]. NATURE-NEW BIOLOGY, 1972, 237 (74): : 144 - &

[2] TOPOISOMERASE-I HAS A STRONG BINDING PREFERENCE FOR A CONSERVED HEXADECAMERIC SEQUENCE IN THE PROMOTOR REGION OF THE RIBOSOMAL-RNA GENE FROM TETRAHYMENA-PYRIFORMIS [J]. NUCLEIC ACIDS RESEARCH, 1985, 13 (05) : 1543 - 1557

[3] CHARACTERIZATION OF A MAMMALIAN MUTANT WITH A CAMPTOTHECIN-RESISTANT DNA TOPOISOMERASE-I [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (16) : 5565 - 5569

[4] ILLEGITIMATE RECOMBINATION MEDIATED BY CALF THYMUS DNA TOPOISOMERASE-II INVITRO [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (07) : 2076 - 2080

[5] POTENTIAL ANTI-TUMOR AGENTS .35. QUANTITATIVE RELATIONSHIPS BETWEEN ANTI-TUMOR (L1210) POTENCY AND DNA-BINDING FOR 4'-(9-ACRIDINYLAMINO)METHANESULFON-M-ANISIDIDE ANALOGS [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (05) : 520 - 525

[6] ANTI-TUMOR ACTIVITY OF SUBSTITUTED 9-ANILINOACRIDINES - COMPARISON OF INVIVO AND INVITRO TESTING SYSTEMS [J]. EUROPEAN JOURNAL OF CANCER, 1981, 17 (06) : 671 - 679

[7] BAGULEY BC, 1982, MOL PHARMACOL, V22, P486

[8] EFFECT OF 1-BETA-D-ARABINOFURANOSYLCYTOSINE (ARA-C) ON NUCLEAR TOPOISOMERASE-II ACTIVITY AND ON THE DNA CLEAVAGE AND CYTO-TOXICITY PRODUCED BY 4'-(9-ACRIDINYLAMINO)METHANESULFON-META-ANISIDIDE (META-AMSA) AND ETOPOSIDE IN META-AMSA-SENSITIVE AND META-AMSA-RESISTANT HUMAN-LEUKEMIA CELLSD [J]. BIOCHEMICAL PHARMACOLOGY, 1987, 36 (23) : 4067 - 4077

[9] BECK WT, 1987, CANCER RES, V47, P5455

[10] DNA BREAKAGE AND CLOSURE BY RAT-LIVER TYPE-1 TOPOISOMERASE - SEPARATION OF THE HALF-REACTIONS BY USING A SINGLE-STRANDED-DNA SUBSTRATE [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (05): : 2883 - 2887

[1] SELECTIVE INTERRUPTION OF HIGH MOLECULAR-WEIGHT RNA SYNTHESIS IN HELA-CELLS BY CAMPTOTHECIN [J]. NATURE-NEW BIOLOGY, 1972, 237 (74): : 144 - &

[2] TOPOISOMERASE-I HAS A STRONG BINDING PREFERENCE FOR A CONSERVED HEXADECAMERIC SEQUENCE IN THE PROMOTOR REGION OF THE RIBOSOMAL-RNA GENE FROM TETRAHYMENA-PYRIFORMIS [J]. NUCLEIC ACIDS RESEARCH, 1985, 13 (05) : 1543 - 1557

[3] CHARACTERIZATION OF A MAMMALIAN MUTANT WITH A CAMPTOTHECIN-RESISTANT DNA TOPOISOMERASE-I [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (16) : 5565 - 5569

[4] ILLEGITIMATE RECOMBINATION MEDIATED BY CALF THYMUS DNA TOPOISOMERASE-II INVITRO [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (07) : 2076 - 2080

[5] POTENTIAL ANTI-TUMOR AGENTS .35. QUANTITATIVE RELATIONSHIPS BETWEEN ANTI-TUMOR (L1210) POTENCY AND DNA-BINDING FOR 4'-(9-ACRIDINYLAMINO)METHANESULFON-M-ANISIDIDE ANALOGS [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (05) : 520 - 525

[6] ANTI-TUMOR ACTIVITY OF SUBSTITUTED 9-ANILINOACRIDINES - COMPARISON OF INVIVO AND INVITRO TESTING SYSTEMS [J]. EUROPEAN JOURNAL OF CANCER, 1981, 17 (06) : 671 - 679

[7] BAGULEY BC, 1982, MOL PHARMACOL, V22, P486

[8] EFFECT OF 1-BETA-D-ARABINOFURANOSYLCYTOSINE (ARA-C) ON NUCLEAR TOPOISOMERASE-II ACTIVITY AND ON THE DNA CLEAVAGE AND CYTO-TOXICITY PRODUCED BY 4'-(9-ACRIDINYLAMINO)METHANESULFON-META-ANISIDIDE (META-AMSA) AND ETOPOSIDE IN META-AMSA-SENSITIVE AND META-AMSA-RESISTANT HUMAN-LEUKEMIA CELLSD [J]. BIOCHEMICAL PHARMACOLOGY, 1987, 36 (23) : 4067 - 4077

[9] BECK WT, 1987, CANCER RES, V47, P5455

[10] DNA BREAKAGE AND CLOSURE BY RAT-LIVER TYPE-1 TOPOISOMERASE - SEPARATION OF THE HALF-REACTIONS BY USING A SINGLE-STRANDED-DNA SUBSTRATE [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (05): : 2883 - 2887