IMMUNOPHILINS AND THE NERVOUS-SYSTEM

被引：174
作者：
SNYDER, SH
SABATINI, DM
机构：
[1] JOHNS HOPKINS UNIV,SCH MED,DEPT PHARMACOL & MOLEC SCI,BALTIMORE,MD 21205
[2] JOHNS HOPKINS UNIV,SCH MED,DEPT PSYCHIAT & BEHAV SCI,BALTIMORE,MD 21205
来源：
NATURE MEDICINE | 1995年 / 1卷 / 01期
关键词：
D O I：
10.1038/nm0195-32
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The search for immunosuppressant drugs to increase the success of organ transplantation led to the discovery of the immunophilins, proteins that interface with a range of signal transduction systems inside cells, especially in the nervous and immune systems. Here we review how these interesting molecules work and consider their therapeutic potential.
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页码：32 / 37
页数：6
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