SYNTHESIS AND CHARACTERIZATION OF A SERIES OF HYDROPHOBIC ANTITUMOR AMINE PLATINUM(II) CARBOXYLATES

被引：5
作者：
KHOKHAR, AR
XU, QY
机构：
[1] Department of Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030
来源：
JOURNAL OF COORDINATION CHEMISTRY | 1990年 / 22卷 / 01期
关键词：
PLATINUM; AMINE; CARBOXYLATE; HYDROPHOBICITY; SYNTHESIS;
D O I：
10.1080/00958979009408207
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
As part of a systematic study, a series of hydrophobic amine platinum(II) carboxylate complexes has been prepared as potential antitumor agents in a liposomal-entrapped form. These complexes have been characterized by elemental analysis, IR, 13C and 195Pt NMR spectroscopic techniques. Effect of ligand donors on NMR chemical shift is briefly discussed. © 1990, Taylor & Francis Group, LLC. All rights reserved.
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页码：53 / 58
页数：6
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