EOSINOPHIL-INDUCED CHRONIC ACTIVE HEPATITIS IN THE IDIOPATHIC HYPEREOSINOPHILIC SYNDROME

被引：12
作者：
FOONG, A
SCHOLES, JV
GLEICH, GJ
KEPHART, GM
HOLT, PR
机构：
[1] ST LUKES HOSP, DIV GASTROENTEROL, 114TH ST & AMSTERDAM AVE, NEW YORK, NY 10025 USA
[2] ST LUKES HOSP, DIV PATHOL, NEW YORK, NY 10025 USA
[3] COLUMBIA UNIV COLL PHYS & SURG, DEPT MED, NEW YORK, NY 10032 USA
[4] MAYO CLIN & MAYO FDN, DEPT IMMUNOL, ROCHESTER, MN 55905 USA
来源：
HEPATOLOGY | 1991年 / 13卷 / 06期
关键词：
D O I：
10.1016/0270-9139(91)92477-P
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
A 19-yr-old man had features of chronic hepatitis with piecemeal necrosis as the sole clinical feature of the idiopathic hypereosinophilic syndrome. Liver biopsy specimens demonstrated the presence of activated eosinophils and, by immunohistochemical staining, major basic protein in areas of hepatic cell damage. The case demonstrates the clinical presentation of the idiopathic hypereosinophilic syndrome as chronic hepatitis and the association between eosinophil infiltration and degranulation with the presence of hepatocyte necrosis.
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页码：1090 / 1094
页数：5
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