MEASUREMENT OF QUININE IN FILTER PAPER-ABSORBED BLOOD BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

被引：23

作者：

MBERU, EK

WARD, SA

WINSTANLEY, PA

WATKINS, WM

机构：

[1] UNIV OXFORD,NUFFIELD DEPT CLIN MED,OXFORD,ENGLAND

[2] KENYA GOVT MED RES CTR,NAIROBI,KENYA

[3] UNIV LIVERPOOL,DEPT PHARMACOL & THERAPEUT,LIVERPOOL L69 3BX,ENGLAND

来源：

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS | 1991年 / 570卷 / 01期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/0378-4347(91)80213-V

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

An adaptation of an existing high-performance liquid chromatographic assay is described for the measurement of quinine, within the therapeutic concentration range, in whole blood. This method, in particular the use of small blood samples which have been dried onto filter paper strips, has advantages for clinical and pharmacokinetic studies in the tropics on children with malaria.

引用

页码：180 / 184

页数：5

共 7 条

[1] QUANTIFICATION OF QUININE IN HUMAN-SERUM BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].