HOLOPROSENCEPHALY - PRENATAL-DIAGNOSIS BY SONOGRAPHY AND MAGNETIC-RESONANCE-IMAGING

被引:5
作者
TOMA, P
COSTA, A
MAGNANO, GM
CARIATI, M
LITUANIA, M
机构
[1] Servizio di Radiologia, Istituto 'giannina Gaslini', Geneva, L. go G. Gaslini
[2] Divisione di Ostetricia E Ginecologia, Istituto 'giannina Gaslini', Geneva, L. go G. Gaslini
关键词
diagnosis; Fetal curarization; Holoprosencephaly; Magnetic resonance imaging; Prenatal;
D O I
10.1002/pd.1970100704
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Magnetic resonance (MR) imaging was performed on two women at the 33rd and 34th pregnancy week, respectively, after ultrasonographic detection of a brain malformation. Fetal neuromuscular blockade was induced by pancuronium bromide injected into the umbilical vein under continuous ultrasound (US) guidance. MR images supported the echotomographic diagnosis of holoprosencephaly, improving the image quality and offering additional information in such cases of difficult differential fetal diagnosis. Holoprosencephaly was finally confirmed by neonatal US and autopsy (case 1), US, CT and MR (case 2). Copyright © 1990 John Wiley & Sons, Ltd.
引用
收藏
页码:429 / 436
页数:8
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