CAN ECT-INDUCED COGNITIVE EFFECTS BE ALTERED PHARMACOLOGICALLY

被引:13
作者
KHAN, A [1 ]
MIROLO, MH [1 ]
MIROLO, HA [1 ]
MILLER, S [1 ]
机构
[1] UNIV WASHINGTON,SCH MED,DEPT PSYCHIAT & BEHAV SCI,SEATTLE,WA 98195
关键词
COGNITIVE DEFICITS; ELECTROCONVULSIVE THERAPY; RESEARCH MODELS;
D O I
10.1016/0278-5846(93)90016-L
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
1. A systematic review of the literature revealed twelve clinical trials that evaluated nine different drugs, and used three different conceptual models to prevent, restore or treat ECT-induced cognitive deficits. 2. This review indicated inconclusive results regarding clinical utility of any of the drugs. 3. Major factors discussed include the complexities involved in the evaluation of ECT-induced cognitive deficits, and the techniques of evaluating changes in cognitive functions. 4. Our conclusion is that future research should emphasize understanding the neural mechanisms related to ECT-induced cognitive deficits. We suggest several areas for future exploration.
引用
收藏
页码:861 / 873
页数:13
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