THE 3D STRUCTURE OF GLUCOSE-OXIDASE FROM ASPERGILLUS-NIGER - IMPLICATIONS FOR THE USE OF GOD AS A BIOSENSOR ENZYME

被引：156

作者：

HECHT, HJ ^{[1
]}

SCHOMBURG, D ^{[1
]}

KALISZ, H ^{[1
]}

SCHMID, RD ^{[1
]}

机构：

[1] GESELL BIOTECHNOL FORSCH MBH,DEPT ENZYME TECHNOL,W-3300 BRAUNSCHWEIG,GERMANY

来源：

BIOSENSORS & BIOELECTRONICS | 1993年 / 8卷 / 3-4期

关键词：

GLUCOSE OXIDASE; X-RAY CRYSTALLOGRAPHY; PROTEIN-3D STRUCTURE; BIOSENSOR;

D O I：

10.1016/0956-5663(93)85033-K

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

The tertiary structure of glucose oxidase (GOD) from Aspergillus niger was determined by x-ray crystallography (to be described elsewhere). The overall folding of the enzyme is described with regard to its application in biosensors, and conclusions are drawn from experiments on electrical communication between the enzyme and the electrodes.

引用

页码：197 / 203

页数：7

共 7 条

[1] FERROCENE-MEDIATED ENZYME ELECTRODE FOR AMPEROMETRIC DETERMINATION OF GLUCOSE [J].

CASS, AEG ;

DAVIS, G ;

FRANCIS, GD ;

HILL, HAO ;

ASTON, WJ ;

HIGGINS, IJ ;

PLOTKIN, EV ;

SCOTT, LDL ;

TURNER, APF .

ANALYTICAL CHEMISTRY, 1984, 56 (04) :667-671

[2] ELECTRODE SYSTEMS FOR CONTINUOUS MONITORING IN CARDIOVASCULAR SURGERY [J].

CLARK, LC ;

LYONS, C .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1962, 102 (01) :29-&

[3] ELECTRICAL COMMUNICATION BETWEEN REDOX CENTERS OF GLUCOSE-OXIDASE AND ELECTRODES VIA ELECTROSTATICALLY AND COVALENTLY BOUND REDOX POLYMERS [J].

DEGANI, Y ;

HELLER, A .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (06) :2357-2358

[4] DIRECT ELECTRICAL COMMUNICATION BETWEEN CHEMICALLY MODIFIED ENZYMES AND METAL-ELECTRODES .2. METHODS FOR BONDING ELECTRON-TRANSFER RELAYS TO GLUCOSE-OXIDASE AND D-AMINO-ACID OXIDASE [J].

DEGANI, Y ;

HELLER, A .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (08) :2615-2620

[5] CRYSTAL-STRUCTURE OF GLUCOSE-OXIDASE FROM ASPERGILLUS-NIGER REFINED AT 2 .3 ANGSTROM RESOLUTION [J].

HECHT, HJ ;

KALISZ, HM ;

HENDLE, J ;

SCHMID, RD ;

SCHOMBURG, D .

JOURNAL OF MOLECULAR BIOLOGY, 1993, 229 (01) :153-172

[6] CRYSTALLIZATION AND PRELIMINARY-X-RAY DIFFRACTION STUDIES OF A DEGLYCOSYLATED GLUCOSE-OXIDASE FROM ASPERGILLUS-NIGER [J].

KALISZ, HM ;

HECHT, HJ ;

SCHOMBURG, D ;

SCHMID, RD .

JOURNAL OF MOLECULAR BIOLOGY, 1990, 213 (02) :207-209

[7]

SCHELLER FW, 1989, STUD BIOPHYS, V132, P93

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