PULSE RADIOLYSIS OF RABBIT LIVER METALLOTHIONEIN IN AQUEOUS SOLUTION

被引：0

作者：

Fang Xingwang ^{[1
]}

Li Fengmei ^{[2
]}

Wu Jilan ^{[1
]}

Di Shaojie ^{[2
]}

Wei Genshuan ^{[1
]}

Ru Bingen ^{[3
]}

机构：

[1] Peking Univ, Dept Tech Phys, Beijing 100871, Peoples R China

[2] Beijing Normal Univ, Inst Low Energy, Beijing 100875, Peoples R China

[3] Peking Univ, Life Sci Ctr, Beijing 100871, Peoples R China

来源：

ACTA PHYSICO-CHIMICA SINICA | 1993年 / 9卷 / 05期

关键词：

Metallothionein; Pulse radiolysis; Radiolysis mechanism;

D O I：

10.3866/PKU.WHXB19930525

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Metallothioneine (MTs) are widely occuring proteins characterized by a low molecular weight (6500-6800) and an extremely high metal and sulfur content. The mechanism of pulse radiolysis of rabbit liver MT-I in aqueous solution was studied. After pulse radiolysis, two peaks occured with maximum absorption at 450nm and 280nm. It was supposed that the first peak was due to RSSR- radical formed by the combination of RS- anion. The observed kinetic constants of growth and decay of RSSR- radical were estimated from the absorption spectra.

引用

页码：702 / 705

页数：4

共 8 条

[1] Barton J.P., 1970, INT J RADIAT PHYS CH, V2, P159
[2] THE PHYSIOLOGICAL-FUNCTION OF METALLOTHIONEIN
BRADY, FO
[J]. TRENDS IN BIOCHEMICAL SCIENCES, 1982, 7 (04) : 143 - 145
[3] PULSE-RADIOLYSIS STUDY OF SULFHYDRYL COMPOUNDS IN AQUEOUS-SOLUTION
HOFFMAN, MZ
HAYON, E
[J]. JOURNAL OF PHYSICAL CHEMISTRY, 1973, 77 (08): : 990 - 996
[4] AMINO-ACID-SEQUENCE OF EQUINE RENAL METALLOTHIONEIN-1B
KOJIMA, Y
BERGER, C
VALLEE, BL
KAGI, JHR
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (10) : 3413 - 3417
[5] DNA-REPAIR IN THE METALLOTHIONEIN GENE INCREASES WITH TRANSCRIPTIONAL ACTIVATION
OKUMOTO, DS
BOHR, VA
[J]. NUCLEIC ACIDS RESEARCH, 1987, 15 (23) : 10021 - 10030
[6] PREVENTION OF ADVERSE-EFFECTS OF GAMMA-RAY IRRADIATION AFTER METALLOTHIONEIN INDUCTION BY BISMUTH SUBNITRATE IN MICE
SATOH, M
MIURA, N
NAGANUMA, A
MATSUZAKI, N
KAWAMURA, E
IMURA, N
[J]. EUROPEAN JOURNAL OF CANCER & CLINICAL ONCOLOGY, 1989, 25 (12): : 1727 - 1731
[7] POSSIBLE ROLE FOR METALLOTHIONEIN IN PROTECTION AGAINST RADIATION-INDUCED OXIDATIVE STRESS - KINETICS AND MECHANISM OF ITS REACTION WITH SUPEROXIDE AND HYDROXYL RADICALS
THORNALLEY, PJ
VASAK, M
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1985, 827 (01) : 36 - 44
[8] METAL THIOLATE CLUSTERS IN COBALT(II)-METALLOTHIONEIN
VASAK, M
KAGI, JHR
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (11): : 6709 - 6713

← 1 →