CARDIOTONIC AGENTS .8. SELECTIVE INHIBITORS OF ADENOSINE 3',5'-CYCLIC PHOSPHATE PHOSPHODIESTERASE-III - ELABORATION OF A 5-POINT MODEL FOR POSITIVE INOTROPIC ACTIVITY

被引：114
作者：
MOOS, WH
HUMBLET, CC
SIRCAR, I
RITHNER, C
WEISHAAR, RE
BRISTOL, JA
MCPHAIL, AT
机构：
[1] WARNER LAMBERT PARKE DAVIS,DIV RES,DEPT PHARMACOL,ANN ARBOR,MI 48105
[2] DUKE UNIV,DEPT CHEM,PAUL M GROSS CHEM LAB,DURHAM,NC 27706
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1987年 / 30卷 / 11期
关键词：
D O I：
10.1021/jm00394a006
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：1963 / 1972
页数：10
相关论文
共 46 条
[1]  
[Anonymous], 1974, INT TABLES XRAY CRYS, VIV
[2]  
BELLAMY LJ, 1975, INFRARED SPECTRA COM, V1, P238
[3]  
BREITMAIER E, 1978, 13C NMR SPECTROSCOPY, P70
[4]   AGENTS FOR THE TREATMENT OF HEART-FAILURE [J].
BRISTOL, JA ;
EVANS, DB .
MEDICINAL RESEARCH REVIEWS, 1983, 3 (03) :259-287
[5]   CARDIOTONIC AGENTS .1. 4,5-DIHYDRO-6-[4-(1H-IMIDAZOL-1-YL)PHENYL]-3(2H)-PYRIDAZINONES - NOVEL POSITIVE INOTROPIC AGENTS FOR THE TREATMENT OF CONGESTIVE HEART-FAILURE [J].
BRISTOL, JA ;
SIRCAR, I ;
MOOS, WH ;
EVANS, DB ;
WEISHAAR, RE .
JOURNAL OF MEDICINAL CHEMISTRY, 1984, 27 (09) :1099-1101
[6]  
CAMPBELL SF, 1984, SPEC PUBL R SOC CHEM, V47
[7]   NEW POSITIVE INOTROPIC AGENTS IN THE TREATMENT OF CONGESTIVE-HEART-FAILURE - MECHANISMS OF ACTION AND RECENT CLINICAL DEVELOPMENTS .2. [J].
COLUCCI, WS ;
WRIGHT, RF ;
BRAUNWALD, E .
NEW ENGLAND JOURNAL OF MEDICINE, 1986, 314 (06) :349-358
[8]   NEW POSITIVE INOTROPIC AGENTS IN THE TREATMENT OF CONGESTIVE-HEART-FAILURE - MECHANISMS OF ACTION AND RECENT CLINICAL DEVELOPMENTS .1. [J].
COLUCCI, WS ;
WRIGHT, RF ;
BRAUNWALD, E .
NEW ENGLAND JOURNAL OF MEDICINE, 1986, 314 (05) :290-299
[9]   IN SEARCH OF THE DIGITALIS REPLACEMENT [J].
ERHARDT, PW .
JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (02) :231-237
[10]   CARDIOVASCULAR PHARMACOLOGY OF THE CARDIOTONIC, IMAZODAN (CL-914) [J].
EVANS, DB ;
POTOCZAK, RE ;
STEFFEN, RP ;
BURMEISTER, WE ;
MCNISH, RW ;
SCHENDEN, JA ;
KAPLAN, HR .
DRUG DEVELOPMENT RESEARCH, 1986, 9 (02) :143-157
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