B-CELL SIGNALING VIA THE C-TYPE LECTINS CD23 AND CD72

被引：81

作者：

GORDON, J

机构：

[1] John Gordon is at the Dept of Immunology, The Medical School, Birmingham, B15 2TT, Vincent Drive

来源：

IMMUNOLOGY TODAY | 1994年 / 15卷 / 09期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0167-5699(94)90270-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Although CD23 and CD72 are well-known B-cell signalling molecules, the intracellular signal transduction pathways through which they operate remain poorly elucidated. This may partly reflect their somewhat dubious histories, with claims and counterclaims being made for functions and ligands. Here, John Gordon discusses why such controversy should surround the two B-cell-associated C-type lectins and provides speculation as to their respective roles in regulating an immune response that may be different in mice and humans.

引用

页码：411 / 417

页数：7

共 48 条

[1] CD21 IS A LIGAND FOR CD23 AND REGULATES IGE PRODUCTION [J].