Antibacterial resin monomers based on quaternary ammonium and their benefits in restorative dentistry

被引：81
作者：
Imazato, Satoshi [1 ]
Chen, Ji-hua [2 ]
Ma, Sai [2 ]
Izutani, Naomi [3 ]
Li, Fang [2 ]
机构：
[1] Osaka Univ, Grad Sch Dent, Dept Biomat Sci, 1-8 Yamadaoka, Suita, Osaka 5650871, Japan
[2] Fourth Mil Med Univ, Sch Stomatol, Dept Prosthodont, Xian 710032, Shaanxi, Peoples R China
[3] Univ Penn, Sch Dent Med, Dept Prevent & Restorat Sci, Philadelphia, PA 19104 USA
来源：
JAPANESE DENTAL SCIENCE REVIEW | 2012年 / 48卷 / 02期
基金：
日本学术振兴会;
关键词：
Dental resins; Monomers; Quaternary ammonium; Antibacterial;
D O I：
10.1016/j.jdsr.2012.02.003
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Antibacterial resin monomers are unique molecules that provide dental resins with "bio-active function'', i.e. the ability to control bacterial infection. They have strong antibacterial activity when unpolymerized and also demonstrate contact inhibitory effects after being polymerized without releasing antibacterial components. Intensive research has been conducted on antibacterial monomers based on quaternary ammonium, such as methacryloyloxydodecylpyridinium bromide ( MDPB), focusing on their basic properties and uses in several resinous restoratives. As represented by successful commercialization of an adhesive system incorporating MDPB, quaternary ammonium based antibacterial monomers have the potential for utilization in various restorative materials and regimens, including caries management and pulp care. (C) 2012 Japanese Association for Dental Science. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：115 / 125
页数：11
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