Antibacterial resin monomers based on quaternary ammonium and their benefits in restorative dentistry

被引：81

作者：

Imazato, Satoshi ^{[1
]}

Chen, Ji-hua ^{[2
]}

Ma, Sai ^{[2
]}

Izutani, Naomi ^{[3
]}

Li, Fang ^{[2
]}

机构：

[1] Osaka Univ, Grad Sch Dent, Dept Biomat Sci, 1-8 Yamadaoka, Suita, Osaka 5650871, Japan

[2] Fourth Mil Med Univ, Sch Stomatol, Dept Prosthodont, Xian 710032, Shaanxi, Peoples R China

[3] Univ Penn, Sch Dent Med, Dept Prevent & Restorat Sci, Philadelphia, PA 19104 USA

来源：

JAPANESE DENTAL SCIENCE REVIEW | 2012年 / 48卷 / 02期

基金：

日本学术振兴会;

关键词：

Dental resins; Monomers; Quaternary ammonium; Antibacterial;

D O I：

10.1016/j.jdsr.2012.02.003

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Antibacterial resin monomers are unique molecules that provide dental resins with "bio-active function'', i.e. the ability to control bacterial infection. They have strong antibacterial activity when unpolymerized and also demonstrate contact inhibitory effects after being polymerized without releasing antibacterial components. Intensive research has been conducted on antibacterial monomers based on quaternary ammonium, such as methacryloyloxydodecylpyridinium bromide ( MDPB), focusing on their basic properties and uses in several resinous restoratives. As represented by successful commercialization of an adhesive system incorporating MDPB, quaternary ammonium based antibacterial monomers have the potential for utilization in various restorative materials and regimens, including caries management and pulp care. (C) 2012 Japanese Association for Dental Science. Published by Elsevier Ltd. All rights reserved.

引用

页码：115 / 125

页数：11

共 78 条

[1]

[Anonymous], 1993, DENT JPN

[2] Synthesis and characterization of dimethacrylates containing quaternary ammonium functionalities for dental applications [J].

Antonucci, Joseph M. ;

Zeiger, Diana N. ;

Tang, Kathy ;

Lin-Gibson, Sheng ;

Fowler, Bruce O. ;

Lin, Nancy J. .

DENTAL MATERIALS, 2012, 28 (02) :219-228

[3] Dental adhesion review: Aging and stability of the bonded interface [J].

Breschi, Loyenzo ;

Mazzoni, Annalisa ;

Ruggeri, Alessandra ;

Cadenaro, Milena ;

Di Lenarda, Robeyto ;

Dorigo, Elettya De Stefano .

DENTAL MATERIALS, 2008, 24 (01) :90-101

[4] Polymerizable semi-fluorinated gemini surfactants designed for antimicrobial materials [J].

Caillier, Laurent ;

de Givenchy, Elisabeth Taffin ;

Levy, Richard ;

Vandenberghe, Yves ;

Geribaldi, Serge ;

Guittard, Frederic .

JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2009, 332 (01) :201-207

[5] Synthesis and antimicrobial properties of polymerizable quaternary ammoniums [J].

Caillier, Laurent ;

de Givenchy, Elisabeth Taffin ;

Levy, Richard ;

Vandenberghe, Yves ;

Geribaldi, Serge ;

Guittard, Frederic .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2009, 44 (08) :3201-3208

[6] Chlorhexidine preserves dentin bond in vitro [J].

Carrilho, M. R. O. ;

Carvalho, R. M. ;

de Goes, M. F. ;

di Hipolito, V. ;

Geraldeli, S. ;

Tay, F. R. ;

Pashley, D. H. ;

Tjaderhane, L. .

JOURNAL OF DENTAL RESEARCH, 2007, 86 (01) :90-94

[7] Surface functionalization technique for conferring antibacterial properties to polymeric and cellulosic surfaces [J].

Cen, L ;

Neoh, KG ;

Kang, ET .

LANGMUIR, 2003, 19 (24) :10295-10303

[8] The bonding property and cytotoxicity of a dental adhesive incorporating a new antibacterial monomer [J].

Chai, Z. ;

Li, F. ;

Fang, M. ;

Wang, Y. ;

Ma, S. ;

Xiao, Y. ;

Huang, L. ;

Chen, J. .

JOURNAL OF ORAL REHABILITATION, 2011, 38 (11) :849-856

[9]

Chan KM, 2003, AM J DENT, V16, P340

[10] Inflammation-regeneration interplay in the dentine-pulp complex [J].

Cooper, Paul R. ;

Takahashi, Yusuke ;

Graham, Lee W. ;

Simon, Stephane ;

Imazato, Satoshi ;

Smith, Anthony J. .

JOURNAL OF DENTISTRY, 2010, 38 (09) :687-697

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