Serum Lipids and Lipoproteins in Non-Diabetic, and Non-Hypertensive Patients of IHD

Background: Atherosclerosis is the most common cause of two main presentations of CAD i.e. angina pectoris (AP) and myocardial infarction (MI). Plasma lipids and lipoproteins abnormalities are frequently associated with the presence of atheroscoerosis CAD. Aim: To evaluate the role of lipids and complete lipoprotein profile in patients of angina pectoris and myocardial infarction with atherosclerosis. Methods: A total of 109 male patients of CAD (AP 42 + MI 67) and 50 healthy control subjects were included in the study. Results: This study found highly significant (P<0.001) raised levels of total cholesterol except in AP, triglycerides, LDL, VLDL and significantly low levels of total HDL cholesterol and MI, when compared with controls. However, only significantly (P<0.02) raised levels discriminated the patients of MI when compared with AP patients. Conclusion: It is concluded that all lipids and lipoproteins play important direct or indirect role in atherosclerosis CAD.