A NOVEL SYNTHESIS OF PROTECTED GLUCOSE INTERMEDIATES

被引：10

作者：

BECKER, D

GALILI, N

机构：

[1] Dept. of Chemistry, Technion-Israel Institute of Technology, Technion City, Haifa

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 33期

关键词：

D O I：

10.1016/S0040-4039(00)61283-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The 1,2,4,6-Tetra-O-pivaloyl-D-gluco-pyranose 3 and 1,2,3,6-Tetra-O-pivaloyl-D-glucopyranose 4 have been prepared in one step from anhydrous glucose and pivaloyl chloride. These new intermediates can be converted into the corresponding esters, or used in the synthesis of a disaccharide in good yield. Thus, 2,3,6-Tri-O-pivaloyl-gluco-pyranose 10 can be prepared from 4, and used for preparation of beta-gluco derivatives via the corresponding trichloroacetimidate 12.

引用

页码：4775 / 4778

页数：4

共 13 条

[1]

Bock K., 1982, ANNU REP NMR SPECTRO, V13, P1

[2]

ELDESOKY ESI, 1990, LIEBIGS ANN CHEM, P877

[3] SELECTIVE CLEAVAGE OF ANOMERIC ACETYL GROUPS OF ACETYLATED GLYCOSYL RESIDUES BY HYDRAZINE [J].