NUCLEOTIDE-SEQUENCE OF THE COMPLEMENTARY-DNA FOR HUMAN PIT-1/GHF-1

被引：41
作者：
TATSUMI, K
NOTOMI, T
AMINO, N
MIYAI, K
机构：
[1] Department of Laboratory Medicine, Osaka University Medical School, Osaka
来源：
BIOCHIMICA ET BIOPHYSICA ACTA | 1992年 / 1129卷 / 02期
关键词：
PIT-1; GHF-1; CDNA SEQUENCE; PITUITARY; (HUMAN);
D O I：
10.1016/0167-4781(92)90494-K
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Human cDNA clones encoding Pit-1/GHF-1, a pituitary-specific DNA binding factor, were obtained by PCR following reverse transcription of human pituitary RNA. It is approx. 1.3 kb in size with 0.1 kb 5' non-coding region, 0.9 kb protein-coding region and 0.3 kb 3' non-coding region. The predicted human Pit-1/GHF-1 peptide structure has 291 amino acids and is highly conserved among mouse, rat and bovine. In addition, the 5' non-coding region is highly conserved with rat pit-1/GHF-1 sequence to the transcription start site.
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页码：231 / 234
页数：4
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