FLAGELLATE ERYTHEMA FROM BLEOMYCIN - WITH HISTOPATHOLOGICAL FINDINGS SUGGESTIVE OF INFLAMMATORY ONCOTAXIS

A case of erythema in a "flagellate" pattern clue to administration of bleomycin in a patient with Hodgkin's disease is described. Emphasis is placed on the low dose of bleomycin administered -15 mg parenterally - and the short time interval between drug administration and beginning of symptoms: 24 h. The histopathological findings were consistent with a mechanism of inflammatory oncotaxis: the attraction of tumor cells by the skin perhaps due to the bleomycin accumulated and the trauma caused by scratching subsequent to pruritus. © 1990 S. Karger AG, Basel.