FLAGELLATE ERYTHEMA FROM BLEOMYCIN - WITH HISTOPATHOLOGICAL FINDINGS SUGGESTIVE OF INFLAMMATORY ONCOTAXIS

被引：32

作者：

CORTINA, P ^{[1
]}

GARRIDO, JA ^{[1
]}

TOMAS, JF ^{[1
]}

UNAMUNO, P ^{[1
]}

ARMIJO, M ^{[1
]}

机构：

[1] UNIV SALAMANCA,HOSP GEN,DEPT HEMATOL,E-37007 SALAMANCA,SPAIN

来源：

DERMATOLOGICA | 1990年 / 180卷 / 02期

关键词：

Bleomycin; Drug reactions; Inflammatory oncotaxis; Flagellate’ erythema;

D O I：

10.1159/000248004

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

A case of erythema in a "flagellate" pattern clue to administration of bleomycin in a patient with Hodgkin's disease is described. Emphasis is placed on the low dose of bleomycin administered -15 mg parenterally - and the short time interval between drug administration and beginning of symptoms: 24 h. The histopathological findings were consistent with a mechanism of inflammatory oncotaxis: the attraction of tumor cells by the skin perhaps due to the bleomycin accumulated and the trauma caused by scratching subsequent to pruritus. © 1990 S. Karger AG, Basel.

引用

页码：106 / 109

页数：4

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