Macular Hole Formation After Intravitreal Ranibizumab Injection in Wet Age-Related Macular Degeneration

被引:11
|
作者
Mukherjee, Chandoshi [1 ]
Mitra, Arijit [1 ]
Kumar, N. Ajith [1 ]
Elsherbiny, Samer [1 ]
Lip, Peck Lin [1 ]
机构
[1] Birmingham & Midland Eye Ctr, City Hosp Dudley Rd, Birmingham B18 7QH, W Midlands, England
来源
OPEN OPHTHALMOLOGY JOURNAL | 2015年 / 9卷
关键词
Full thickness macular hole; intravitreal ranibizumab injection; pigment epithelial detachment; posterior vitreous traction; wet age-related macular degeneration;
D O I
10.2174/1874364101509010177
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Ranibizumab is a monoclonal antibody fragment that inhibits angiogenesis by inhibiting vascular endothelial growth factor A, used as a treatment for patients with wet aged-related macular degeneration (ARMD). Adverse effects from intravitreal Ranibizumab injections are well recognised. Macular hole formation following Ranibizumab injection is a complication that has been recently reported in few case reports. We present a larger case series of five patients, who developed full thickness macular holes (FTMH) after intravitreal Ranibizumab injections for treatment of wet ARMD that we were aware of between 2009 and 2013.
引用
收藏
页码:177 / 180
页数:4
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