P53 - AT THE CROSSROADS OF MOLECULAR CARCINOGENESIS AND RISK ASSESSMENT

被引：476
作者：
HARRIS, CC
机构：
[1] Laboratory of Human Carcinogenesis, Division of Cancer Etiology, National Cancer Institute, Bethesda
来源：
SCIENCE | 1993年 / 262卷 / 5142期
关键词：
D O I：
10.1126/science.8266092
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
[No abstract available]
引用
收藏
页码：1980 / 1981
页数：2
相关论文
共 41 条
[1]   AFLATOXIN-B(1) INDUCES THE TRANSVERSION OF G-]T IN CODON 249 OF THE P53 TUMOR-SUPPRESSOR GENE IN HUMAN HEPATOCYTES [J].
AGUILAR, F ;
HUSSAIN, SP ;
CERUTTI, P .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (18) :8586-8590
[2]  
[Anonymous], 1993, ISSUES RISK ASSESSME
[3]  
BARRETT JC, 1992, PROG CLIN BIOL RES, V376, P1
[4]   GENE SPECIFIC DNA-REPAIR [J].
BOHR, VA .
CARCINOGENESIS, 1991, 12 (11) :1983-1992
[5]  
BOYLE JO, 1993, CANCER RES, V53, P4477
[6]   A ROLE FOR SUNLIGHT IN SKIN-CANCER - UV-INDUCED P53 MUTATIONS IN SQUAMOUS-CELL CARCINOMA [J].
BRASH, DE ;
RUDOLPH, JA ;
SIMON, JA ;
LIN, A ;
MCKENNA, GJ ;
BADEN, HP ;
HALPERIN, AJ ;
PONTEN, J .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (22) :10124-10128
[7]   SELECTIVE G-MUTATION TO T-MUTATION OF P53 GENE IN HEPATOCELLULAR-CARCINOMA FROM SOUTHERN AFRICA [J].
BRESSAC, B ;
KEW, M ;
WANDS, J ;
OZTURK, M .
NATURE, 1991, 350 (6317) :429-431
[8]   PREFERENTIAL REPAIR AND STRAND-SPECIFIC REPAIR OF BENZO[A]PYRENE DIOL EPOXIDE ADDUCTS IN THE HPRT GENE OF DIPLOID HUMAN FIBROBLASTS [J].
CHEN, RH ;
MAHER, VM ;
BROUWER, J ;
VANDEPUTTE, P ;
MCCORMICK, JJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (12) :5413-5417
[9]   THYMOCYTE APOPTOSIS INDUCED BY P53-DEPENDENT AND INDEPENDENT PATHWAYS [J].
CLARKE, AR ;
PURDIE, CA ;
HARRISON, DJ ;
MORRIS, RG ;
BIRD, CC ;
HOOPER, ML ;
WYLLIE, AH .
NATURE, 1993, 362 (6423) :849-852
[10]   MICE DEFICIENT FOR P53 ARE DEVELOPMENTALLY NORMAL BUT SUSCEPTIBLE TO SPONTANEOUS TUMORS [J].
DONEHOWER, LA ;
HARVEY, M ;
SLAGLE, BL ;
MCARTHUR, MJ ;
MONTGOMERY, CA ;
BUTEL, JS ;
BRADLEY, A .
NATURE, 1992, 356 (6366) :215-221
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