THE CONTROL OF HOMOLOGOUS LYSIS

被引：173
作者：
LACHMANN, PJ
机构：
[1] Molecular Immunopathology Unit, MRC Centre, Cambridge, CB2 2QH, Hills Road
来源：
IMMUNOLOGY TODAY | 1991年 / 12卷 / 09期
关键词：
D O I：
10.1016/0167-5699(91)90005-E
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Complement activation unleashes powerful effector mechanisms against which host cells are protected by homologous restriction factors. These factors are glycolipid-anchored membrane proteins that either induce C3 convertase dissociation (for example decay-accelerating factor) or prevent the full development of the membrane attack complex (for example homologous restriction factor and CD59). In this article Peter Lachmann explores the biology and biochemistry o f these important and intriguing molecules. © 1991.
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页码：312 / 315
页数：4
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