MORPHICEPTIN (NH4-TYR-PRO-PHE-PRO-CONH2) - A POTENT AND SPECIFIC AGONIST FOR MORPHINE (MU) RECEPTORS

被引：367

作者：

CHANG, KJ ^{[1
]}

KILLIAN, A ^{[1
]}

HAZUM, E ^{[1
]}

CUATRECASAS, P ^{[1
]}

CHANG, JK ^{[1
]}

机构：

[1] PENINSULA LABS,SAN CARLOS,CA 94070

来源：

SCIENCE | 1981年 / 212卷 / 4490期

关键词：

D O I：

10.1126/science.6259732

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：75 / 77

页数：3

共 19 条

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[2] MATERIAL WITH OPIOID ACTIVITY IN BOVINE-MILK AND MILK-PRODUCTS [J].

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[3]

CHANG K, UNPUBLISHED

[4] POSSIBLE ROLE OF DISTINCT MORPHINE AND ENKEPHALIN RECEPTORS IN MEDIATING ACTIONS OF BENZOMORPHAN DRUGS (PUTATIVE-KAPPA AND SIGMA-AGONISTS) [J].

CHANG, KJ ;

HAZUM, E ;

CUATRECASAS, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (08) :4469-4473

[5]

CHANG KJ, 1979, J BIOL CHEM, V254, P2610

[6]

CHANG KJ, 1979, MOL PHARMACOL, V16, P91

[7]

CHANG KJ, MOL PHARMACOL

[8] OPIATE RECEPTOR-BINDING AFFECTED DIFFERENTIALLY BY OPIATES AND OPIOID PEPTIDES [J].

CHILDERS, SR ;

CREESE, I ;

SNOWMAN, AM ;

SNYDER, SH .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1979, 55 (01) :11-18

[9] GUANINE NUCLEOTIDES DIFFERENTIATE AGONIST AND ANTAGONIST INTERACTIONS WITH OPIATE RECEPTORS [J].

CHILDERS, SR ;

SNYDER, SH .

LIFE SCIENCES, 1978, 23 (07) :759-761

[10] MULTIPLE OPIATE RECEPTOR-SITES ON PRIMARY AFFERENT-FIBERS [J].

FIELDS, HL ;

EMSON, PC ;

LEIGH, BK ;

GILBERT, RFT ;

IVERSEN, LL .

NATURE, 1980, 284 (5754) :351-353

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