SEQUENCE OF THE 5'-FLANKING REGION OF THE GENE ENCODING HUMAN MUSCLE GLYCOGEN-SYNTHASE

被引：0

作者：

NAKAYAMA, T ^{[1
]}

ESUMI, M ^{[1
]}

NAKABAYASHI, H ^{[1
]}

机构：

[1] NIHON UNIV, SCH MED, MED RES INST, ITABASHI KU, TOKYO 173, JAPAN

来源：

GENE | 1994年 / 150卷 / 02期

关键词：

PROMOTER; DIABETES; GENOMIC LIBRARY; MICROSATELLITE; CA-REPEAT; POLYMORPHISM; TATA-LESS; POLYMERASE CHAIN REACTION;

D O I：

暂无

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The 5'-flanking region of the gene encoding human muscle glycogen synthase was isolated from a human placental genomic library and sequenced. The sequence is TATA-less and G+C-rich, and putative transcription-controlling sequences were identified. Furthermore, a simple (dC-dA)(n) sequence repeat was identified about 4 kb upstream from the start codon. This sequence was highly polymorphic and five alleles were typed in the Japanese population using the polymerase chain reaction.

引用

页码：391 / 393

页数：3

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