SEQUENCE OF THE 5'-FLANKING REGION OF THE GENE ENCODING HUMAN MUSCLE GLYCOGEN-SYNTHASE

被引：0
|
作者：
NAKAYAMA, T [1 ]
ESUMI, M [1 ]
NAKABAYASHI, H [1 ]
机构：
[1] NIHON UNIV, SCH MED, MED RES INST, ITABASHI KU, TOKYO 173, JAPAN
来源：
GENE | 1994年 / 150卷 / 02期
关键词：
PROMOTER; DIABETES; GENOMIC LIBRARY; MICROSATELLITE; CA-REPEAT; POLYMORPHISM; TATA-LESS; POLYMERASE CHAIN REACTION;
D O I：
暂无
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The 5'-flanking region of the gene encoding human muscle glycogen synthase was isolated from a human placental genomic library and sequenced. The sequence is TATA-less and G+C-rich, and putative transcription-controlling sequences were identified. Furthermore, a simple (dC-dA)(n) sequence repeat was identified about 4 kb upstream from the start codon. This sequence was highly polymorphic and five alleles were typed in the Japanese population using the polymerase chain reaction.
引用
收藏
页码：391 / 393
页数：3
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