MULTICENTER COMPARISON OF IN-VITRO ACTIVITIES OF FK-037, CEFEPIME, CEFTRIAXONE, CEFTAZIDIME, AND CEFUROXIME

被引：41
|
作者：
WASHINGTON, JA
JONES, RN
GERLACH, EH
MURRAY, PR
ALLEN, SD
KNAPP, CC
机构：
[1] UNIV IOWA HOSP & CLIN,IOWA CITY,IA 52242
[2] ST FRANCIS REG MED CTR,WICHITA,KS 67214
[3] WASHINGTON UNIV,MED CTR,ST LOUIS,MO 63130
[4] INDIANA UNIV,MED CTR,INDIANAPOLIS,IN 46223
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1993年 / 37卷 / 08期
关键词：
D O I：
10.1128/AAC.37.8.1696
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
In a multicenter study, the MICs of FK-037 for 90% of the strains tested (MIC90s) were less-than-or-equal-to 1 mug/ml for members of the family Enterobacteriaceae other than Citrobacter freundii, Enterobacter spp., and Serratia marcescens. Activity against Pseudomonas aeruginosa was variable, with a MIC50 and a MIC90 of 4 and 32 mug/ml, respectively. Relative to cefepime, however, FK-037 was less active against ceftazidime-resistant isolates of Enterobacter cloacae. The MIC90 of FK-037 for methicillin-resistant staphylococci was > 16 mug/ml.
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页码：1696 / 1700
页数：5
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