RESULTS OF MULTIMODAL THERAPY IN EWINGS-SARCOMA - A RETROSPECTIVE ANALYSIS OF 20 PATIENTS

被引：2
|
作者：
BENARUSH, M
KUTEN, A
PEREZNAHUM, M
COHEN, Y
BIALIK, V
机构：
[1] NO ISRAEL ONCOL CTR,RAMBAM MED CTR,RADIOTHERAPY UNIT,IL-35254 HAIFA,ISRAEL
[2] RAMBAM MED CTR,DEPT ORTHOPED,HAIFA,ISRAEL
[3] TECHNION ISRAEL INST TECHNOL,FAC MED,HAIFA,ISRAEL
[4] BEN GURION UNIV NEGEV,FAC MED,SOROKA MED CTR,DEPT ONCOL,IL-84105 BEER SHEVA,ISRAEL
[5] NO ISRAEL ONCOL CTR,PEDIAT ONCOL UNIT,IL-35254 HAIFA,ISRAEL
来源：
JOURNAL OF SURGICAL ONCOLOGY | 1991年 / 48卷 / 01期
关键词：
VACA CHEMOTHERAPY; SURGERY; RADIOTHERAPY; CENTRAL SKELETAL LESIONS; PERIPHERAL SKELETAL LESIONS;
D O I：
10.1002/jso.2930480110
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
A retrospective analysis was performed of 20 patients with Ewing's sarcoma treated by combined modality therapy, consisting of surgery, radiotherapy, and chemotherapy. Fourteen patients (70%) achieved complete remission and 5 patients (25%) were in partial remission at the end of treatment. One patient (5%) failed to respond to combined modality therapy. The overall 5 year actuarial survival was 64% and the disease free survival, 55%. Persistent or recurrent disease occurred in 8 patients (40%); one of them was salvaged by surgery and chemotherapy. Site and extent of primary lesion were prognosticators of patients' outcome. One patient developed radiation-related-sequelae. The efficacy of aggressive management consisting of wide surgery, radiotherapy and intermittent high dose chemotherapy is discussed.
引用
收藏
页码：51 / 55
页数：5
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