MISUSE OF ZOPICLONE AND CONVULSIONS DURING WITHDRAWAL

被引：22
作者：
ARANKO, K
HENRIKSSON, M
HUBLIN, C
SEPPALAINEN, AM
机构：
[1] UNIV HELSINKI, DEPT PSYCHIAT, SF-00100 HELSINKI 10, FINLAND
[2] UNIV HELSINKI, DEPT NEUROL, SF-00100 HELSINKI 10, FINLAND
[3] UNIV HELSINKI, CENT HOSP, SF-00100 HELSINKI 10, FINLAND
来源：
PHARMACOPSYCHIATRY | 1991年 / 24卷 / 04期
关键词：
D O I：
10.1055/s-2007-1014457
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
It has been documented that benzodiazepines have the potential to cause dependence and withdrawal reactions, including convulsions. However, the available data concerning zopiclone, a nonbenzodiazepine hypnotic, are insufficient. The present study describes the case of a 36-year-old man who repeatedly misused zopiclone, in daily doses of 60 - 90 mg. Furthermore, the patient suffered from convulsion on two occasions following abrupt withdrawal of zopiclone. The concomitant use of alcohol, trimipramine, and promazine may have contributed to the development of convulsions. It is concluded that zopiclone may cause problems associated with misuse and withdrawal reactions similar to those of benzodiazepines.
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收藏
页码：138 / 140
页数：3
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