DIAMINES INTERFERE WITH THE TRANSPORT OF L-ORNITHINE IN EHRLICH-CELL PLASMA-MEMBRANE VESICLES

被引：20

作者：

MEDINA, MA

URDIALES, JL

DECASTRO, IN

SANCHEZJIMENEZ, F

机构：

[1] Lab. de Bioquim. y Biol. Mol., Facultad de Ciencias, Universidad de Malaga

来源：

BIOCHEMICAL JOURNAL | 1991年 / 280卷

关键词：

D O I：

10.1042/bj2800825

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. L-Ornithine transport by plasma-membrane vesicles isolated from Ehrlich cells is Na+-independent and shows a saturable and a diffusional component. 2. Putrescine, histamine, 5-hydroxytryptamine and 2,3-diaminopropane at 55-mu-M concentration significantly inhibit 0.5 mM-L-ornithine transport, at least for the first 10 min of incubation. 3. There is a trans-stimulatory effect of putrescine on L-orthinine transport.

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收藏

页码：825 / 827

页数：3

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