ISOLATION OF HOMOGENEOUS PHOSPHOLIPASE-A2 FROM HUMAN-PLATELETS

被引：65

作者：

APITZCASTRO, RJ ^{[1
]}

MAS, MA ^{[1
]}

CRUZ, MR ^{[1
]}

JAIN, MK ^{[1
]}

机构：

[1] UNIV DELAWARE,DEPT CHEM,NEWARK,DE 19711

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 91卷 / 01期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0006-291X(79)90583-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Phospholipase A2 from human blood platelets has been purified to homogeneity by treatment of the platelet homogenate with H2SO4, followed by affinity chromatography of the extract. The platelet phospholipase is a soluble, heat-stable protein of MW 44000. The purified enzyme inhibits ADP-induced platelet aggregation. © 1979.

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页码：63 / 71

页数：9

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