AMINO ACID TRANSPORT BY CHOROID PLEXUS IN VITRO

被引：55

作者：

LORENZO, AV

CUTLER, RWP

机构：

[1] Children's Hospital Medical Center, Departments of Pharmacology and Neurology, Harvard Medical School, Boston, Massachusetts

来源：

JOURNAL OF NEUROCHEMISTRY | 1969年 / 16卷 / 04期

关键词：

D O I：

10.1111/j.1471-4159.1969.tb06857.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Choroid plexus from mongrel cats was incubated from 1 to 120 min in artificial cerebrospinal fluid containing α‐amino[1‐14C]isobutyric acid. The uptake of α‐amino [1‐14C]isobutyric acid occurred against a concentration gradient, was saturable, dependent on metabolic energy, and inhibited by natural amino acids. These results indicate that a transport mechanism is present in choroid plexus which could serve to regulate amino acid concentration in the cerebrospinal fluid of animals. Copyright © 1969, Wiley Blackwell. All rights reserved

引用

页码：577 / &

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