CONFIGURATIONAL ANALYSIS OF RHYNCHOPHYLLINE-TYPE OXINDOLE ALKALOIDS - ABSOLUTE CONFIGURATION OF CILIAPHYLLINE RHYNCHOCILINE SPECIONOXEINE ISOSPECIONOXEINE ROTUNDIFOLINE AND ISOROTUNDIFOLINE

被引：58

作者：

TRAGER, WF

LEE, CM

PHILLIPSON, JD

HADDOCK, RE

DWUMABAD.D

BECKETT, AH

机构：

[1] Department of Pharmacy, Chelsea College of Science and Technology, University of London, Chelsea

来源：

TETRAHEDRON | 1968年 / 24卷 / 02期

关键词：

D O I：

10.1016/0040-4020(68)88002-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

From a general configurational and conformational analysis of rhynchophyllinoid alkaloids, unique physical criteria are developed that differentiate between the 8 possible configurational types. The criteria are applied to 6 rhynchophylline-type alkaloids of unknown configurations and show that ciliaphylline, specionoxeine and isorotundifoline have the normal B configuration while rhynchociline, isospecionoxeine and rotundifoline have the normal A configuration. All 6 alkaloids have the C15Hα absolute stereochemistry. © 1968.

引用

页码：523 / +

页数：1

共 26 条

[11] MEVALONOID NATURE OF VINDOLINE AND RESERPININE [J].