COMPARISON OF CONVENTIONAL AND THINPREP PREPARATIONS OF MUCOID CYTOLOGY SAMPLES

被引：32

作者：

HEES, K

LEBEAU, PB

机构：

[1] Institute for Pathology, Merheim, Cologne

[2] Cytyc Corp, Marlborough, Massachusetts

来源：

DIAGNOSTIC CYTOPATHOLOGY | 1995年 / 12卷 / 02期

关键词：

MUCOID CYTOLOGICAL SAMPLES; CONVENTIONAL SEDIMENT SMEARS OR SACCAMANNO PREPARATIONS; THINPREP METHOD; CYTOLOGY SCREENING EFFICIENCY; DIAGNOSTIC SENSITIVITY;

D O I：

10.1002/dc.2840120221

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Cytological specimens containing large amounts of mucus and/or blood are often a considerable problem as far as preparation and especially screening are concerned. The ThinPrep(TM) method, which uses a mucolytic and hemolysing solution and prepares slides automatically, eliminates difficulties in both areas. Comparing ThinPreps to conventionally prepared samples reveals equivalent or even superior cellular preservation. Cells are spread in a thin layer, mostly with only a minimal amount of residual mucus or blood. Screening is consequently much easier and faster. The time-saving effect does not compromise the diagnostic accuracy, as we could demonstrate with an 92% overall agreement in both procedures. The difference of 8% could possibly be attributed to inadequate splitting of the samples. (C) 1995 Wiley-Liss, Inc.

引用

页码：181 / 185

页数：5

共 4 条

[1]

Hutchinson ML, Agarwal P, Denault T, Berger B, Cibras ES, A new look at cervical cytology, Acta Cytol, 36, pp. 499-504, (1992)

[2]

Papillo JL, Lee KR, Manna EA, Clinical evaluation of the ThinPrep method for the preparation of nongynecologic material, Acta Cytol, 36, pp. 651-652, (1992)

[3]

Rizzo T, Schumann BG, Riching JM, Comparison of the pick‐and‐smear and Saccamanno methods for sputum cytologic analysis, Acta Cytol, 34, pp. 875-880, (1990)

[4]

Hall S, Wu T-C, Sherman M, Erozan Y, Suitability of ThinPrep specimens for immunocytochemistry and gene amplification by polymerase chain reaction, Acta Cytol, 36, (1992)

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