INCREASE OF CELL-SURFACE HYALURONIC-ACID DURING AGING IN HUMAN-LIVER CELLS

被引：5
|
作者：
BERNARD, B
FONT, J
AUBERY, M
BAFFET, G
GUILLOUZO, A
机构：
[1] FAC MED PARIS, INSERM, U 180, RECH BIOL & PATHOL MOLEC GLYCOPROTEINES GRP, F-75006 PARIS, FRANCE
[2] HOP PONTCHAILLOU, INSERM, U 49, UNITE RECH HEPATOL, F-35011 RENNES, FRANCE
来源：
MECHANISMS OF AGEING AND DEVELOPMENT | 1982年 / 19卷 / 03期
关键词：
D O I：
10.1016/0047-6374(82)90055-0
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Fetal and newborn human liver cells exhibit 2 classes of Ricinus communis lectin binding site in the early passages; these cells at the late passages and adult cells have only 1 class of binding site. Hyaluronidase treatment of both fetal and newborn old cells and adult cells results in recovery of the 2 classes of binding site and in release of higher amounts of hyaluronic acid. Increased hyaluronic acid might play an important role in age-related cell membrane changes.
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页码：211 / 216
页数：6
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