Synthesis of tetracyclic dibenzo[b,f][1,4] oxazepine-fused β-lactams via visible-light-induced Staudinger annulation

被引：0

作者：

Wang, Jiao-Mei ^{[1
]}

Zhao, Yu ^{[2
]}

Li, Wen-Ping ^{[3
]}

Kong, Xiang-Jun ^{[1
]}

Yao, Chang-Sheng ^{[3
]}

Zhang, Kai ^{[3
]}

机构：

[1] Xuzhou Univ Technol, Sch Mat & Chem Engn, Xuzhou 221018, Jiangsu, Peoples R China

[2] Yanan Univ, Coll Chem & Chem Engn, Yanan 716000, Shanxi, Peoples R China

[3] Jiangsu Normal Univ, Sch Chem & Mat Sci, Jiangsu Key Lab Green Synthet Chem Funct Mat, Xuzhou 221116, Jiangsu, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2023年

基金：

中国国家自然科学基金;

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient visible-light-induced Staudinger [2 + 2] annulation reaction between a-diazo ketones and dibenzo[b,f][1,4]oxazepine/thiazepine-imines under catalyst-free conditions has been developed. This protocol provides a facile method to synthesize tetracyclic dibenzo[b,f][1,4]oxazepine/thiazepine-fused beta-lactams bearing a quaternary carbon center with a broad substrate scope and high efficiency (37 examples, up to >99% yield).

引用

页数：9

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