ENANTIOSELECTIVE DEOXYGENATION OF ALKYL ARYL SULFOXIDES BY DMSO REDUCTASE FROM RHODOBACTER-SPHAEROIDES FS DENITRIFICANS

被引：20

作者：

ABO, M ^{[1
]}

TACHIBANA, M ^{[1
]}

OKUBO, A ^{[1
]}

YAMAZAKI, S ^{[1
]}

机构：

[1] UNIV TOKYO, DEPT APPL BIOL CHEM, BUNKYO KU, TOKYO 113, Japan

来源：

BIOORGANIC & MEDICINAL CHEMISTRY | 1995年 / 3卷 / 02期

关键词：

D O I：

10.1016/0968-0896(95)00004-Z

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The substrate specificity and enantioselectivity of DMSO reductase from Rhodobacter sphaeroides f.s. denitrificans were studied on a series of alkyl aryl sulfoxides as substrate. The enzyme was found to catalyze deoxygenation of (S)-sulfoxides predominantly. (R)-Sulfoxides were recovered with a high enantiomeric excess.

引用

页码：109 / 112

页数：4

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