Fractal dimension of the breast cancer cells resistant and sensitive to doxorubicin activity

被引：0

作者：

Medviediev, O. ^{[1
]}

Gorobets, O. Yu. ^{[1
]}

Chekhun, V. F. ^{[2
]}

Gorobets, S. V. ^{[1
]}

Demyanenko, I. V. ^{[1
]}

Butenko, K. O. ^{[1
]}

机构：

[1] Natl Tech Univ, Kyiv Polytech Inst, 37 Prospect Peremogy, UA-03056 Kiev, Ukraine

[2] R Kavetsky Inst Expt Pathol Oncol & Radiobiol, 45 Vasylkivska St, UA-03022 Kiev, Ukraine

来源：

FUNCTIONAL MATERIALS | 2016年 / 23卷 / 01期

关键词：

fractal dimension; doxorubicin; MCF-line breast cancer cells; BMN;

D O I：

10.15407/fm23.01.049

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

The main purpose of this research is examining and comparing of the fractal dimension (FD) and quantity of biogenic magnetic nanoparticles (BMN) of the resistant and sensitive MCF-line breast cancer cells to doxorubicin activity. The FD of boundaries of sensitive cells is greater than the FD of the boundaries of resistant cells. The quantity of BMN per one cell in sensitive and resistant cells do not differ. The FD of the cell boundaries can be an additional marker for the determination of cell sensitivity to the doxorubicin activity. The part of the tumor cell surface containing one BMN can be also the potential marker for the determination of the sensitivity to the doxorubicin action as well.

引用

页码：49 / 54

页数：6

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