BELGRADE AND HANTAAN HANTAVIRUSES - THE CAUSATIVE AGENTS OF SEVERE HEMORRHAGIC-FEVER WITH RENAL SYNDROME IN CHILDREN IN SERBIA

被引：2
作者：
BOGDANOVIC, R
GLIGIC, A
NIKOLIC, V
OGNJANOVIC, M
MARKOVIC, M
SARJANOVIC, L
机构：
[1] Institute of Mother and Child Health of Serbia, Belgrade, Belgrade, 11070
[2] Institute of Immunology and Virology Torlak, Belgrade
来源：
PEDIATRIC NEPHROLOGY | 1994年 / 8卷 / 03期
关键词：
BELGRADE AND HANTAAN HANTAVIRUSES; HEMORRHAGIC FEVER; ACUTE RENAL FAILURE;
D O I：
10.1007/BF00866341
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
During an outbreak of haemorrhagic fever with renal syndrome (HERS) in 1989, five children (3 girls, 2 boys, aged 6.8-16 years) with a severe form of the disease were treated; four of these were followed for 22-28 months. The main clinical features in all five patients were: fever, headache, myalgia, abdominal and back pain and vomiting; haemorrhagic syndrome was present in four children. Renal syndrome presented with severe acute renal failure in all five patients. All patients recovered. Serological confirmation by an indirect immunofluorescence assay, by enzyme immunoassay for IgM antibodies and by plaque reduction neutralization test showed infection by Belgrade virus in three and by Hantaan virus in two patients. It was not possible to differentiate these two serogroups on the basis of clinical features. This study provides further information on the circulation of different hantaviruses causing severe HERS in Serbia.
引用
收藏
页码：299 / 303
页数：5
相关论文
共 31 条
  • [1] Lee H.W., Epidemiology, Manual of hemorrhagic fever with renal syndrome, pp. 41-48, (1989)
  • [2] Trencseni T., Keleti B., Clinical aspects and epidemiology of haemorrhagic fever with renal syndrome. Analysis of clinical and epidemiological experiences in Hungary, (1971)
  • [3] van Ypersele de Strihou C., Mery J.P., Hantavirus-related acute interstitial nephritis in western Europe. Expansion of a world-wide zoonosis, Q J Med, 73, pp. 941-950, (1989)
  • [4] Settergren B., Leschinskaya E., Zagidullin I., Fazlyeva R., Khunafina D., Niklasson B., Hemorrhagic fever with renal syndrome: comparison of clinical course in Sweden and in the Western Soviet Union, Scand J Infect Dis, 23, pp. 549-552, (1991)
  • [5] Settergren B., Nephropathia epidemica (hemorrhagic fever with renal syndrome) in Scandinavia, Rev Infect Dis, 13, pp. 736-744, (1991)
  • [6] Pilaski J., Ellerich C., Kreutzer T., Lang A., Benik W., Pohl-Koppe A., Bode L., Vanek E., Autenrieth I.B., Bigos K., Lee H.W., Haemorrhagic fever with renal syndrome in Germany, Lancet, 337, (1991)
  • [7] Rollin P.E., Courdrier D., Saluzzo J.F., Sureau P., Hemorrhagic fever with renal syndrome in France: update (abstract), Am J Trop Med Hyg, 45, pp. 151-152, (1991)
  • [8] Antoniades A., LeDuc J.W., Daniel-Alexiou S., Clinical and epidemiological aspects of hemorrhagic fever with renal syndrome (HFRS) in Greece, Eur J Epidemiol, 3, pp. 295-301, (1987)
  • [9] Chumakov M., Shindarov L., Gavrilovska I., Vasilenko S., Gorbachova E., Katzorov S., Seroepidemiology of HFRS in Bulgaria, Acta Virol (Praha), 32, pp. 261-267, (1988)
  • [10] Lukac V., Obradovic M., Gligic A., Stojanovic R., Rakovic-Savcic L., Diglisic G., Drndarevic D., Djordjevic D., Haemorrhagic fever with renal syndrome in Yugoslavia in the period 1951–1988, Vojnosanit Pregl, 32, pp. 261-267, (1989)
1234