THE 1ST SYNTHESIS OF A MOENOMYCIN-TYPE TRANSGLYCOSYLASE INHIBITOR

被引:16
|
作者
LUNING, J
MOLLER, U
MULLER, D
WELZEL, P
MARKUS, A
VANHEIJENOORT, Y
VANHEIJENOORT, J
机构
[1] RUHR UNIV BOCHUM,FAK CHEM,D-44780 BOCHUM,GERMANY
[2] HOECHST AG,D-65926 FRANKFURT,GERMANY
[3] UNIV PARIS 11,F-91405 ORSAY,FRANCE
关键词
D O I
10.1016/S0040-4020(01)81550-7
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Starting from chitobiose octaacetate, D-galacturonic acid derivative 3, and D-glyceric acid derived building block 7, the moenomycin trisaccharide analogue 8c has been synthesized. 8c is an as active transglycosylase inhibitor as moenomycin A.
引用
收藏
页码:10587 / 10596
页数:10
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