Comparing efficiencies of diclofenac sodium and paracetamol in patients with primary dysmenorrhea pain by using Visual Analog Scale

被引:10
作者
Ayan, Murat [1 ]
Tas, Ufuk [2 ]
Sogut, Erkan [3 ]
Arici, Semih [4 ]
Karaman, Serkan [4 ]
Esen, Mehmet [1 ]
Demirturk, Fazli [5 ]
机构
[1] Gaziosmanpasa Univ, Fac Med, Dept Emergency Med, Tokat, Turkey
[2] Gaziosmanpasa Univ, Fac Med, Dept Anat, Tokat, Turkey
[3] Gaziosmanpasa Univ, Fac Med, Dept Biochem, Tokat, Turkey
[4] Gaziosmanpasa Univ, Fac Med, Dept Anesthesiol & Reanimat, Tokat, Turkey
[5] Gaziosmanpasa Univ, Fac Med, Dept Obstet & Gynecol, Tokat, Turkey
来源
AGRI-THE JOURNAL OF THE TURKISH SOCIETY OF ALGOLOGY | 2013年 / 25卷 / 02期
关键词
Pain; diclofenac sodium; paracetamol; primer dysmenorrhea; VAS;
D O I
10.5505/agri.2013.42103
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives: The aim of this study was to compare the efficiency of diclofenac sodium to paracetamol using a visual analog scale in the patients presenting to the emergency room with primary dysmenorrhea. Methods: Group I (n= 40) patients were diagnosed with primary dysmenorrhea and treated with paracetamol (1 gr intravenous) and Group II (n= 40) patients were diagnosed with primary dysmenorrhea and treated with diclofenac sodium (75 mg intramuscular). In both groups, patients were 19-30 years old. In all groups, the intensity of the pain was ranked from 0 (no pain) to 10 (intolerable) using VAS. The VAS scores were compared between treatment groups. Results: Between two groups, there was no statistically significant difference in age, mean arterial pressure and pulse values. The initial VAS values of the first group were higher than that of 2nd group. Following treatment, in the 10th and 30th minutes, the VAS values were lower in Group I than Group II (p= 0.00). The VAS values of each group were significantly different from each other on the 10th and 30th minutes. VAS values at the 10th and 30th minutes were lower compared to the initial values and the values in the 30th minute were lower relative to the 10th minute (p= 0.00) in both treatment groups. Conclusion: We can suggest that paracetamol is more efficient than diclofenac sodium in the treatment of primary dysmenorrhea.
引用
收藏
页码:78 / 82
页数:5
相关论文
共 21 条
  • [1] New insights into the mechanism of action of acetaminophen:: Its clinical pharmacologic characteristics reflect its inhibition of the two prostaglandin H2 synthases
    Aronoff, DM
    Oates, JA
    Boutaud, O
    [J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 2006, 79 (01) : 9 - 19
  • [2] Intravenous Paracetamol or Morphine for the Treatment of Renal Colic: A Randomized, Placebo-Controlled Trial
    Bektas, Firat
    Eken, Cenker
    Karadeniz, Ozgur
    Goksu, Erkan
    Cubuk, Metin
    Cete, Yildiray
    [J]. ANNALS OF EMERGENCY MEDICINE, 2009, 54 (04) : 568 - 574
  • [3] Berek, 2011, NOBEL TIP KITABEVI
  • [4] Effect of a low-dose oral contraceptive containing 20 μg ethinylestradiol and 150 μg desogestrel on dysmenorrhea
    Callejo, J
    Díaz, J
    Ruiz, A
    García, RM
    [J]. CONTRACEPTION, 2003, 68 (03) : 183 - 188
  • [5] Coco AS, 1999, AM FAM PHYSICIAN, V60, P489
  • [6] STUDIES WITH PAIN RATING-SCALES
    DOWNIE, WW
    LEATHAM, PA
    RHIND, VM
    WRIGHT, V
    BRANCO, JA
    ANDERSON, JA
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 1978, 37 (04) : 378 - 381
  • [7] Erdine S, 2007, AGRI, P37
  • [8] Graham Garry G, 2005, Am J Ther, V12, P46, DOI 10.1097/00045391-200501000-00008
  • [9] Harel Zeev, 2006, J Pediatr Adolesc Gynecol, V19, P363, DOI 10.1016/j.jpag.2006.09.001
  • [10] Harel Zeev, 2002, Paediatr Drugs, V4, P797