DETERMINANTS OF GLOMERULAR CROSS-SECTIONAL AREA

被引：8
|
作者：
NEWBOLD, KM
HOWIE, AJ
机构：
[1] Department of Pathology, University of Birmingham, Birmingham
来源：
JOURNAL OF PATHOLOGY | 1990年 / 162卷 / 04期
关键词：
GLOMERULUS; MORPHOMETRY; GLOBAL SCLEROSIS;
D O I：
10.1002/path.1711620409
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
A method of measurement of glomerular cross-sectional area was applied to 267 renal biopsies from 19 groups of patients with well-defined pathological and clinical conditions. There was a correlation between the mean glomerular area for each group and the percentage of global sclerosis in each group. A few groups had glomeruli that were larger than would be expected from their percentage of global sclerosis, probably due to cellular proliferation and/or infiltration. A few groups had glomeruli that were smaller than would be expected from their percentage of global sclerosis, probably due to ischaemic shrinkage. These observations indicate that as well as the known influence of body size on the glomerular area, the number of functioning glomeruli in the body has an important effect on the glomerular area.
引用
收藏
页码：329 / 332
页数：4
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