PROTON MAGNETIC RESONANCE SPECTRA OF GLUCAGON AT 220 MHZ

被引：8

作者：

BAK, B

LED, JJ

PEDERSEN, EJ

机构：

[1] Chemical Laboratory V, University of Copenhagen, Copenhagen

来源：

JOURNAL OF MOLECULAR SPECTROSCOPY | 1969年 / 32卷 / 01期

关键词：

D O I：

10.1016/0022-2852(69)90149-0

中图分类号：

O64 [物理化学（理论化学）、化学物理学]; O56 [分子物理学、原子物理学];

学科分类号：

070203 ; 070304 ; 081704 ; 1406 ;

摘要：

The 1HMR spectra of the polypeptide glucagon (29 amino acid residues) dissolved in CF3COOH, and of deuterated glucagon dissolved in CF3COOD were recorded at 220 MHz. A total of 214 observable proteon resonances were assigned to 15 spectral bands I-XV. About 65 proton resonances were assigned to spectral lines of width 5-10 cps, or to narrow spectral regions. Good agreement with earlier obtained data for insulin and its A- and B-chain S-sulfonates was obtained. Spectral effects of the slow conversion of glucagon to heptatri-fluoroacetylated glucagon were found and utilized in the assignment of the spectrum of natural glucagon. © 1969.

引用

页码：151 / &