DIFFERENTIAL REGULATION OF PI HYDROLYSIS AND ADENYLYL CYCLASE BY MUSCARINIC RECEPTOR SUBTYPES

被引：731
作者：
PERALTA, EG
ASHKENAZI, A
WINSLOW, JW
RAMACHANDRAN, J
CAPON, DJ
机构：
[1] GENENTECH INC,DEPT DEV BIOL,SAN FRANCISCO,CA 94080
[2] UNIV CALIF SAN FRANCISCO,DEPT BIOCHEM & BIOPHYS,SAN FRANCISCO,CA 94143
来源：
NATURE | 1988年 / 334卷 / 6181期
关键词：
D O I：
10.1038/334434a0
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：434 / 437
页数：4
相关论文
共 30 条
[1]   AN M2 MUSCARINIC RECEPTOR SUBTYPE COUPLED TO BOTH ADENYLYL CYCLASE AND PHOSPHOINOSITIDE TURNOVER [J].
ASHKENAZI, A ;
WINSLOW, JW ;
PERALTA, EG ;
PETERSON, GL ;
SCHIMERLIK, MI ;
CAPON, DJ ;
RAMACHANDRAN, J .
SCIENCE, 1987, 238 (4827) :672-675
[2]   INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL - 2 INTERACTING 2ND MESSENGERS [J].
BERRIDGE, MJ .
ANNUAL REVIEW OF BIOCHEMISTRY, 1987, 56 :159-193
[3]   LITHIUM AMPLIFIES AGONIST-DEPENDENT PHOSPHATIDYLINOSITOL RESPONSES IN BRAIN AND SALIVARY-GLANDS [J].
BERRIDGE, MJ ;
DOWNES, CP ;
HANLEY, MR .
BIOCHEMICAL JOURNAL, 1982, 206 (03) :587-595
[4]   MUSCARINIC RECEPTOR SUBCLASSES [J].
BIRDSALL, NJM ;
HULME, EC .
TRENDS IN PHARMACOLOGICAL SCIENCES, 1983, 4 (11) :459-463
[5]   HUMAN CDNA CLONES FOR AN ALPHA-SUBUNIT OF GI SIGNAL-TRANSDUCTION PROTEIN [J].
BRAY, P ;
CARTER, A ;
GUO, V ;
PUCKETT, C ;
KAMHOLZ, J ;
SPIEGEL, A ;
NIRENBERG, M .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (15) :5115-5119
[6]   ROLE OF GUANINE-NUCLEOTIDE BINDING-PROTEIN IN THE ACTIVATION OF POLYPHOSPHOINOSITIDE PHOSPHODIESTERASE [J].
COCKCROFT, S ;
GOMPERTS, BD .
NATURE, 1985, 314 (6011) :534-536
[7]   MULTIPLE, DISTINCT FORMS OF BOVINE AND HUMAN PROTEIN-KINASE-C SUGGEST DIVERSITY IN CELLULAR SIGNALING PATHWAYS [J].
COUSSENS, L ;
PARKER, PJ ;
RHEE, L ;
YANGFENG, TL ;
CHEN, E ;
WATERFIELD, MD ;
FRANCKE, U ;
ULLRICH, A .
SCIENCE, 1986, 233 (4766) :859-866
[8]   CLONING OF THE GENE AND CDNA FOR MAMMALIAN BETA-ADRENERGIC-RECEPTOR AND HOMOLOGY WITH RHODOPSIN [J].
DIXON, RAF ;
KOBILKA, BK ;
STRADER, DJ ;
BENOVIC, JL ;
DOHLMAN, HG ;
FRIELLE, T ;
BOLANOWSKI, MA ;
BENNETT, CD ;
RANDS, E ;
DIEHL, RE ;
MUMFORD, RA ;
SLATER, EE ;
SIGAL, IS ;
CARON, MG ;
LEFKOWITZ, RJ ;
STRADER, CD .
NATURE, 1986, 321 (6065) :75-79
[9]   CONSTRUCTION AND CHARACTERIZATION OF AN ACTIVE FACTOR-VIII VARIANT LACKING THE CENTRAL 1/3 OF THE MOLECULE [J].
EATON, DL ;
WOOD, WI ;
EATON, D ;
HASS, PE ;
HOLLINGSHEAD, P ;
WION, K ;
MATHER, J ;
LAWN, RM ;
VEHAR, GA ;
GORMAN, C .
BIOCHEMISTRY, 1986, 25 (26) :8343-8347
[10]   MOLECULAR DISTINCTION BETWEEN MUSCARINIC ACETYLCHOLINE-RECEPTOR SUBTYPES [J].
FUKUDA, K ;
KUBO, T ;
AKIBA, I ;
MAEDA, A ;
MISHINA, M ;
NUMA, S .
NATURE, 1987, 327 (6123) :623-625
123