CONDUCTING POLYMER-BASED BIOSENSORS

被引：90

作者：

CONTRACTOR, AQ

SURESHKUMAR, TN

NARAYANAN, R

SUKEERTHI, S

LAL, R

SRINIVASA, RS

机构：

[1] INDIAN INST TECHNOL, DEPT ELECT ENGN, BOMBAY 400076, INDIA

[2] INDIAN INST TECHNOL, CTR MAT SCI, BOMBAY 400076, INDIA

来源：

ELECTROCHIMICA ACTA | 1994年 / 39卷 / 8-9期

关键词：

CONDUCTING POLYMER; BIOSENSOR; GLUCOSE; UREA; LIPID; HEMOGLOBIN;

D O I：

10.1016/0013-4686(94)E0054-4

中图分类号：

O646 [电化学、电解、磁化学];

学科分类号：

081704 ;

摘要：

The electronic conductivity of polymers such as polyaniline exhibits a strong dependence on the redox and protonation state of the polymer. This property has been utilised to develop a generic biosensor concept. The concept involves immobilization of the appropriate enzyme in the conducting polymer matrix. The enzyme catalyzed reaction of the biomolecule results in a change in redox potential and/or pH of the micro environment in the polymer matrix. This change in the micro environment triggers a change in the electronic conductivity which is monitored. Results shall be presented which provide proof of the above concept. The systems chosen for investigation are glucose/glucose oxidase, urea/urease, neutral lipid/lipase and hemoglobin/pepsin.

引用

页码：1321 / 1324

页数：4

共 17 条

[1] The estimation of pepsin, trypsin, papain, and cathepsin with hemoglobin [J].