DERMABRASION - THERAPY AND PROPHYLAXIS OF THE PHOTOAGED FACE

被引:60
作者
BENEDETTO, AV
GRIFFIN, TD
BENEDETTO, EA
HUMENIUK, HM
机构
[1] MED COLL PENN, DEPT MED, DIV DERMATOL, PHILADELPHIA, PA 19129 USA
[2] HOSP UNIV PENN, DEPT DERMATOL, PHILADELPHIA, PA 19104 USA
[3] HAHNEMANN UNIV, DEPT MED, DIV DERMATOL, PHILADELPHIA, PA 19102 USA
[4] MED COLL OHIO, TOLEDO, OH 43699 USA
关键词
D O I
10.1016/0190-9622(92)70214-Z
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background: For many years dermabrasion has been used for the treatment of photoaged facial skin. However, there is a paucity of correlative studies that document the beneficial histopathologic effects of dermabrasion with clinical changes. Moreover, long-term follow-up and comparative studies that document these therapeutic results are lacking. Objective: Our purpose was to study patients with photoaged facial skin by comparing the preoperative and postoperative clinical and histopathologic changes that occur as a result of surgical dermabrasion of aged and photodamaged facial skin. Methods: Twelve patients 40 years of age and older with significant photoaging and dermatoheliosis were treated with full-face dermabrasion. Predermabrasion biopsy specimens were compared with matched postdermabrasion biopsy specimens taken at various time intervals from 6 months to 8 years after dermabrasion. Results: Microscopic normalization of the actinically damaged epidermis and papillary dermis was manifested clinically by the replacement of dermatoheliosis with supple, smooth-textured facial skin that remained clinically evident well beyond 8 years after dermabrasion. In addition, the necessity for the continued treatment of premalignant and malignant lesions was virtually eliminated during the 8-year postdermabrasion period. Conclusion: Not only is dermabrasion a beneficial therapeutic option for aged and photodamaged skin, but it also is a valid means of prophylaxis against neoplastic changes.
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页码:439 / 447
页数:9
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