COMPARISON OF PARTIAL DENATURATION MAPS WITH THE KNOWN SEQUENCE OF SIMIAN VIRUS-40 AND PHI-X174 REPLICATIVE FORM DNA

被引：35

作者：

FUNNELL, BE ^{[1
]}

INMAN, RB ^{[1
]}

机构：

[1] UNIV WISCONSIN,DEPT BIOCHEM,MADISON,WI 53706

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1979年 / 131卷 / 02期

关键词：

D O I：

10.1016/0022-2836(79)90079-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Electron microscope partial denaturation maps of two viral DNAs, simian virus 40 and φX174 replicative form, have been obtained. A simple computer program has been developed to predict denaturation maps from any given DNA sequence, based on the percentage of A · T base-pairs along the molecule. Maps constructed from the SV40 DNA and φX174 replicative form DNA base sequence show a good correlation with the experimental maps. The results show that the regions of a DNA molecule that denature first are, in fact, those regions with the highest content of adenine and thymine base-pairs. © 1979.

引用

收藏

页码：331 / 340

页数：10

相关论文

共 50 条

[21] PRODUCTION OF SPECIFIC FRAGMENTS OF PHI-X174 REPLICATIVE FORM DNA BY A RESTRICTION ENZYME FROM HAEMOPHILUS-PARAINFLUENZAE, ENDONUCLEASE HP [J].

JOHNSON, PH ;

LEE, AS ;

SINSHEIMER, RL .

JOURNAL OF VIROLOGY, 1973, 11 (04) :596-599

[22] METHYLATION OF BACTERIOPHAGE PHI-X174 DNA AND ITS POSSIBLE ROLE IN VIRUS MATURATION [J].

GOREN, D ;

KRAMER, J ;

FRIEDMANN, J ;

RAZIN, A .

ISRAEL JOURNAL OF MEDICAL SCIENCES, 1975, 11 (11) :1207-1208

[23] 12 PURIFIED PROTEINS IN RECONSTITUTION OF PHAGE PHI-X174 DNA CONVERSION TO DUPLEX FORM [J].

UEDA, K .

FEDERATION PROCEEDINGS, 1976, 35 (07) :1417-1417

[24] CONVERSION OF SIMIAN VIRUS-40 DNA TO OPEN CIRCULAR FORM BY PHOSPHONOACETIC ACID [J].

BARZILAI, R ;

ITIN, A .

ISRAEL JOURNAL OF MEDICAL SCIENCES, 1978, 14 (07) :819-819

[25] COINFECTION OF ESCHERICHIA-COLI WITH PHAGES G4 AND PHI-X174 - ORIGIN OF DIMERIC REPLICATIVE FORM SPECIES [J].

THOMPSON, BJ ;

SUSSMAN, CH ;

WARNER, RC .

VIROLOGY, 1978, 87 (01) :212-215

[26] FORMATION OF PHI-X174 CATENATED AND CIRCULAR DIMERIC REPLICATIVE DNA BEFORE AND AFTER A SHIFT FROM LIGHT TO HEAVY MEDIUM [J].

HOFS, EBH ;

BAAS, PD ;

JANSZ, HS ;

VANARKEL, GA .

GENETICS, 1973, 74 (JUN) :S117-S118

[27] PRESENCE OF RECOMBINANT FIGURE-8 DIMERS IN REPLICATIVE FORM DNA FROM CO-INFECTION WITH PHAGES PHI-X174 AND G4 [J].

THOMPSON, BJ ;

WARNER, RC .

FEDERATION PROCEEDINGS, 1976, 35 (07) :1417-1417

[28] ELECTRON-MICROSCOPIC DETERMINATION OF THE PREFERENTIAL BINDING-SITES OF ESCHERICHIA-COLI RNA-POLYMERASE TO PHI-X174 REPLICATIVE FORM DNA [J].

WILLIAMS, RC ;

FISHER, HW .

JOURNAL OF MOLECULAR BIOLOGY, 1980, 140 (03) :435-439

[29] LATE REPLICATIVE INTERMEDIATES ARE ACCUMULATED DURING SIMIAN VIRUS-40 DNA-REPLICATION INVIVO AND INVITRO [J].

SEIDMAN, MM ;

SALZMAN, NP .

JOURNAL OF VIROLOGY, 1979, 30 (02) :600-609

[30] NUCLEOTIDE-SEQUENCE OF REPETITIVE MONKEY DNA FOUND IN DEFECTIVE SIMIAN VIRUS-40 [J].

ROSENBERG, M ;

SEGAL, S ;

KUFF, EL ;

SINGER, MF .

CELL, 1977, 11 (04) :845-857

← 1 2 3 4 5 →