STRUCTURE AND PHYSICAL MAP OF THE GENOME OF PARMA WALLABY HERPESVIRUS

被引:13
|
作者
JOHNSON, MA [1 ]
WHALLEY, JM [1 ]
机构
[1] MACQUARIE UNIV,SCH BIOL SCI,SYDNEY 2109,AUSTRALIA
关键词
PARMA WALLABY HERPESVIRUS; MACROPODID HERPESVIRUS-1; GENOME STRUCTURE; PHYSICAL MAP; CLONING;
D O I
10.1016/0168-1702(90)90088-S
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The DNA of parma wallaby herpesvirus (macropodid herpesvirus 1; MHV-1) was analysed by restriction mapping and Southern hybridizations, and clones of EcoRI and SalI fragments were prepared which represented approximately 85% of the genome. It has a length of about 135 kbp consisting of a long unique sequence joined to a short unique sequence bounded by inverted repeat sequences, and occurs as 2 isomers. These findings place MHV-1 in the herpesvirus structural classification Group D, along with equine herpesvirus 1 and pseudorabies virus, and differentiates it from the other known herpesvirus of Australian marsupials.
引用
收藏
页码:41 / 48
页数:8
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