AMYOTROPHIC-LATERAL-SCLEROSIS - THYROID AND PROLACTIN HORMONE CHANGES IN THYROTROPIN-RELEASING-HORMONE THERAPY

被引：1
作者：
TESTA, D
CHIODINI, PG
GIROTTI, F
ATTANASIO, R
机构：
[1] OSPED NIGUARDA CA GRANDA,DIV ENDOCRINOL,MILAN,ITALY
[2] IST NAZL NEUROL C BESTA,DIV NEUROL,I-20133 MILAN,ITALY
来源：
ITALIAN JOURNAL OF NEUROLOGICAL SCIENCES | 1990年 / 11卷 / 06期
关键词：
AMYOTROPHIC LATERAL SCLEROSIS; PROLACTIN; TRIIODOTHYRONINE; THYROXINE; THYROTROPIN; THYROTROPIN-RELEASING HORMONE;
D O I：
10.1007/BF02337445
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
13 patients with amyotrophic lateral sclerosis (ALS) were treated with intravenous infusion of thyrotropin-releasing hormone (TRH). In 6 patients 2 mg/day of TRH was i.v. given over 2 hours for 10 days. In 7 others 2 mg/day of TRH was continuously infused by means of a pump. An increase of thyroid hormones related to the duration of the treatment was observed. A surprising finding was the onset of prolactin (PRL) response to growth hormone releasing hormone (GHRH), previously absent.
引用
收藏
页码：601 / 603
页数：3
相关论文
共 11 条
[1]  
BANDA R, 1985, Neurology, V35, P93
[2]   CHANGES IN GROWTH-HORMONE (GH) SECRETION INDUCED BY HUMAN PANCREATIC GH RELEASING HORMONE-44 IN ACROMEGALY - A COMPARISON WITH THYROTROPIN-RELEASING-HORMONE AND BROMOCRIPTINE [J].
CHIODINI, PG ;
LIUZZI, A ;
DALLABONZANA, D ;
OPPIZZI, G ;
VERDE, GG .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1985, 60 (01) :48-52
[3]  
ENGEL WK, 1983, LANCET, V2, P73
[4]   SUSTAINED RISES IN SERUM THYROTROPIN, THYROXINE, AND TRIIODOTHYRONINE DURING LONG-TERM, CONTINUOUS THYROTROPIN-RELEASING-HORMONE TREATMENT IN PATIENTS WITH AMYOTROPHIC-LATERAL-SCLEROSIS [J].
KAPLAN, MM ;
TAFT, JA ;
REICHLIN, S ;
MUNSAT, TL .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1986, 63 (04) :808-814
[5]   ALTERATIONS IN RECEPTORS FOR THYROTROPIN-RELEASING-HORMONE, SEROTONIN, AND ACETYLCHOLINE IN AMYOTROPHIC LATERAL SCLEROSIS [J].
MANAKER, S ;
CAINE, SB ;
WINOKUR, A .
NEUROLOGY, 1988, 38 (09) :1464-1474
[6]   AMYOTROPHIC-LATERAL-SCLEROSIS - EFFECTS OF ACUTE INTRAVENOUS AND CHRONIC SUBCUTANEOUS ADMINISTRATION OF THYROTROPIN-RELEASING-HORMONE IN CONTROLLED TRIALS [J].
MITSUMOTO, H ;
SALGADO, ED ;
NEGROSKI, D ;
HANSON, MR ;
SALANGA, VD ;
WILBER, JF ;
WILBOURN, AJ ;
BREUER, AC ;
LEATHERMAN, J .
NEUROLOGY, 1986, 36 (02) :152-159
[7]  
MITSUMOTO H, 1984, ANN NEUROL, V16, P109
[8]  
NICOLL RA, 1978, J PHARMACOL EXP THER, V207, P817
[9]   ADMINISTRATION OF GUANIDINE IN AMYOTROPHIC LATERAL SCLEROSIS [J].
NORRIS, FH ;
CALANCHINI, PR ;
FALLAT, RJ ;
PANCHARI, S ;
JEWETT, B .
NEUROLOGY, 1974, 24 (08) :721-728
[10]  
SERRATRICE G, 1986, REV NEUROL, V142, P133
12