BIOMONITORING OF WORKERS EXPOSED TO PESTICIDES

被引:12
作者
BOLOGNESI, C
PARRINI, M
REGGIARDO, G
MERLO, F
BONASSI, S
机构
[1] CSTA Center for the Study of Cancers of Environmental Origin, IST Istituto Nazinale per la Ricerca sul Cancro, Genoa
关键词
CYTOGENETIC; FLORICULTURE; OCCUPATION; PESTICIDES; RISK;
D O I
10.1007/BF00381337
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The potential clastogenic effects of pesticides was investigated in 71 floriculturists exposed to complex chemical mixtures. Exposed and referent subjects were selected from the same geographical area located in north western Italy. A significant association between micronuclei frequency and occupational exposure to pesticides was found (RR = 1.25). A positive dose-response gradient was observed with years of employment (used as an index of cumulative exposure) as a floriculturist. Individuals working exclusively in greenhouses (confined spaces) showed higher micronuclei levels than subjects working in open fields. The study supports the hypothesis that human exposure to pesticides causes a clastogenic damage.
引用
收藏
页码:S185 / S187
页数:3
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